More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Raloxifene 4-glucuronide

Raloxifene 4-glucuronide

HY-135582
MedChem Express
CAS Number182507-22-8
DownloadMSDS
Product group Chemicals
Molecular Weight649.71
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    Raloxifene 4-glucuronide [182507-22-8]
  • Delivery Days Customer
    10
  • CAS Number
    182507-22-8
  • Certification
    Research Use Only
  • Molecular Formula
    C34H35NO10S
  • Molecular Weight
    649.71
  • Scientific Description
    Raloxifene 4-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4-glucuronide binds to estrogen receptor with an IC 50 of 370 microM. [1] [2] . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFbeta3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression [3] .
  • SMILES
    O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=CC=C(C3=C(C(C4=CC=C(OCCN5CCCCC5)C=C4)=O)C6=CC=C(O)C=C6S3)C=C2
  • UNSPSC
    12352200