RANK antibody [7G22]

GeneTex

RANK antibody [7G22]

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

7G22

500 ug/ml

Unconjugated

TNFRSF11A

TNF receptor superfamily member 11a

CD265; familial expansile osteolysis; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; ODFR; OFE; OPTB7; osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; RANK; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; TRANCE receptor; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Mouse

IgG2

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]

Human

2°C to 8°C,-20°C or -80°C

12352203