RANK antibody

GeneTex

RANK antibody

9

Based on internal testing, this antibody is specific for RNAK (TNFRSF11A) and does not cross with OPG (TNFRSF11B).

Western Blot

Research Use Only

Polyclonal

1.06 mg/ml

Unconjugated

TNFRSF11A

TNF receptor superfamily member 11a

CD265; familial expansile osteolysis; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; ODFR; OFE; OPTB7; osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; RANK; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; TRANCE receptor; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Rabbit

IgG

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells. [provided by RefSeq]

Human

2°C to 8°C,-20°C or -80°C

12352203