RANK/TNFRSF11A, Rat (HEK293, Fc)

MedChem Express

RANK/TNFRSF11A, Rat (HEK293, Fc)

10

Research Use Only

95.40

TNF receptor superfamily member 11A

RANK (TNFRSF11A) is a receptor activator of nuclear factor kappaB (NF-kappaB), which is involved in bone metabolism and immune system function. RANK is mainly expressed by osteoblasts/stromal cells, and is associated with the formation of giant cell tumor of bone (GCTBs) [1] . RANK combined with RANKL ligand activated the RANKL/RANK/ OPG system to regulate bone resorption [2] . RANKL/RANK is also a regulator of dendritic cell (DC)-T cell interaction, which is associated with mammary epithelial formation and central nervous system thermoregulation in lactating female [3] [4] . RANK/TNFRSF11A Protein, Rat (HEK293, Fc) produced by HEK293 cells with C-terminal hFc-tag.

-20°C

12352202