Rap1B deltaC, Ras-proximate 1B, deletion of 17 C-terminal residues, human, recombinant, E. coli

Jena Bioscience

Rap1B deltaC, Ras-proximate 1B, deletion of 17 C-terminal residues, human, recombinant, E. coli

5

Research Use Only

Rap (Ras-proximate) proteins are GTPases that belong to the Ras superfamily of small GTP binding proteins. Rap1B is known to antagonize the mitotic and transforming activity of Ras. Rap1B can be activated by cAMP known to either stimulate or inhibit cell proliferation. The deletion of 17 C-terminal amino acids in Rap1B deltaC leads to the loss of the phosphorylation site Ser179 and the geranyl-geranylation site. Protein preparation is 53% GDP- and 47% GTP-loaded, measured by HPLC.

-80°C

41116133