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RAP2A antibody [N1C3-2]

Research Use Only
GTX108831
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetRAP2A
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    RAP2A antibody [N1C3-2]
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5911
  • Target name
    RAP2A
  • Target description
    RAP2A, member of RAS oncogene family
  • Target synonyms
    KREV; K-REV; RAP2; RAP2, member of RAS oncogene family (K-rev); ras-related protein Rap-2a; RbBP-30
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells. Takino JI et al., 2019 Nov 13, Sci Rep
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  • Coiled-coil domain containing protein 124 is a novel centrosome and midbody protein that interacts with the Ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis. Telkoparan P et al., 2013, PLoS One
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