Rapamycin
HY-10219
Overview
- SupplierMedChem Express
- Product NameRapamycin [53123-88-9]
- Delivery Days Customer10
- CAS Number53123-88-9
- CertificationResearch Use Only
- Estimated Purity99.94
- Molecular FormulaC51H79NO13
- Molecular Weight914.17
- Scientific DescriptionRapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 [1] . Rapamycin is an autophagy activator, an immunosuppressant [2] .
- SMILESO=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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