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Rapamycin

HY-10219
MedChem Express
CAS Number53123-88-9
Product group Chemicals
Estimated Purity99.94
Molecular Weight914.17
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Rapamycin [53123-88-9]
  • Delivery Days Customer
    10
  • CAS Number
    53123-88-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C51H79NO13
  • Molecular Weight
    914.17
  • Scientific Description
    Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 [1] . Rapamycin is an autophagy activator, an immunosuppressant [2] .
  • SMILES
    O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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