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Rapamycin-d3 [392711-19-2]

HY-10219S
MedChem Express
CAS Number392711-19-2
Product group Chemicals
Estimated Purity95.3%
Molecular Weight917.19
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Rapamycin-d3 [392711-19-2]
  • Delivery Days Customer
    10
  • CAS Number
    392711-19-2
  • Estimated Purity
    95.3%
  • Molecular Formula
    C51H76D3NO13
  • Molecular Weight
    917.19
  • Scientific Description
    Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2].
  • SMILES
    O=C([C@@]1(O[C@@H](CC[C@H]1C)C[C@@H](/C(C)=C/C=C/C=C/[C@H](C2)C)OC([2H])([2H])[2H])O)C(N3[C@@H](CCCC3)C(O[C@@H](CC([C@@H](/C=C([C@H]([C@H](C([C@@H]2C)=O)OC)O)\C)C)=O)[C@@H](C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)=O)=O
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200