RASA3 antibody [C2C3], C-term

GeneTex

RASA3 antibody [C2C3], C-term

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

RASA3

RAS p21 protein activator 3

GAP1IP4BP, GAPIII, ras GTPase-activating protein 3, GTPase activating protein III, GTPase-activating protein 1 family, inositol 1,3,4,5-tetrakisphosphate-binding protein, Ins(1,3,4,5)P4-binding protein, ins P4-binding protein

Rabbit

IgG

Ras GTPase-activating protein 3

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203