Rasfonin [303156-68-5] [303156-68-5]

Bioss

Rasfonin [303156-68-5] [303156-68-5]

16

303156-68-5

Research Use Only

Unconjugated

>95%

C25H38O6

434.6

Selective apoptosis inducer in ras-dependent cells. Autophagy (Akt-dependent), apoptosis and necroptosis inducer in renal cancer cell lines. Induces death of ras-mutated pancreatic tumor (Panc-1) cells in vitro and in vivo. Robust inhibitor of pancreatic cancers with the K-ras mutation. Reduced Sos1 expression and depressed Ras-MAPK activity.

O=C1O[C@@]([C@H](C[C@@H](C)C/C(C)=C/C)C)([H])C(OC(/C=C/C(C)=C/[C@@H](CO)CCO)=O)C=C1

-20°C

12161509