Rasfonin [303156-68-5]

AdipoGen Life Sciences

Rasfonin

10

6.1

303156-68-5

Research Use Only

>95%

Liquid

Warning

C25H38O6

434.6

Chemical. CAS: 303156-68-5. Formula: C25H38O6. MW: 434.6. Isolated from Trichurus sp. Selective apoptosis inducer in ras-dependent cells. Autophagy (Akt-dependent), apoptosis and necroptosis inducer in renal cancer cell lines. Induces death of ras-mutated pancreatic tumor (Panc-1) cells in vitro and in vivo. Robust inhibitor of pancreatic cancers with the K-ras mutation. Reduced Sos1 expression and depressed Ras-MAPK activity. - Selective apoptosis inducer in ras-dependent cells. Autophagy (Akt-dependent), apoptosis and necroptosis inducer in renal cancer cell lines. Induces death of ras-mutated pancreatic tumor (Panc-1) cells in vitro and in vivo. Robust inhibitor of pancreatic cancers with the K-ras mutation. Reduced Sos1 expression and depressed Ras-MAPK activity.

O=C1O[C@@]([C@H](C[C@@H](C)C/C(C)=C/C)C)([H])C(OC(/C=C/C(C)=C/[C@@H](CO)CCO)=O)C=C1

-20°C,2°C to 8°C

2811

12352200