RASGRP3 Antibody

Aviva Systems Biology

RASGRP3 Antibody

23

WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200

Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Liquid

RASGRP3

RAS guanyl releasing protein 3

GRP3, ras guanyl-releasing protein 3, CalDAG-GEFIII, RAS guanyl releasing protein 3 (calcium and DAG-regulated), calcium and DAG-regulated guanine nucleotide exchange factor III, calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III, guanine nucleotide exchange factor for Rap1

Rabbit

IgG

Ras guanyl-releasing protein 3

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]

Human, Mouse

-20°C

41116161