
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA068151(RASSF1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
RASSF1 Antibody
CSB-PA068151
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetRASSF1
Overview
- SupplierCusabio
- Product NameRASSF1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11186
- Target nameRASSF1
- Target descriptionRas association domain family member 1
- Target synonyms123F2; cardiac-specific ras association domain family 1 protein; NORE2A; pancreas-specific ras association domain family 1 protein; Ras association (RalGDS/AF-6) domain family member 1; ras association domain-containing protein 1; RASSF1A; RDA32; REH3P21; tumor suppressor protein RDA32; WUGSC:H_LUCA12.5
- HostRabbit
- IsotypeIgG
- Protein IDQ9NS23
- Protein NameRas association domain-containing protein 1
- Scientific DescriptionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161