RASSF5 Antibody

Cusabio

RASSF5 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

RASSF5

Ras association domain family member 5

Maxp1; new ras effector 1; NORE1; NORE1A; NORE1B; novel Ras effector 1; Rap1-binding protein; RAPL; Ras association (RalGDS/AF-6) domain family 5; Ras association (RalGDS/AF-6) domain family member 5; ras association domain-containing protein 5; Ras effector-like protein; RASSF3; regulator for cell adhesion and polarization enriched in lymphoid tissue; tumor suppressor RASSF3

Rabbit

IgG

Ras association domain-containing protein 5

Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

-20°C or -80°C

12352203