RASSF5 Antibody

Cusabio

RASSF5 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

RASSF5

Ras association domain family member 5

Maxp1, NORE1, NORE1A, NORE1B, RAPL, RASSF3, ras association domain-containing protein 5, Rap1-binding protein, Ras association (RalGDS/AF-6) domain family 5, Ras association (RalGDS/AF-6) domain family member 5, Ras effector-like protein, new ras effector 1, novel Ras effector 1, regulator for cell adhesion and polarization enriched in lymphoid tissue, tumor suppressor RASSF3

Rabbit

IgG

Ras association domain-containing protein 5

Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Human

-20°C or -80°C

41116161