Rat CD130 / gp130 ELISA Kit
ARG82111
Product group Assays
Overview
- SupplierArigo Biolaboratories
- Product NameRat CD130 / gp130 ELISA Kit
- Delivery Days Customer23
- ApplicationsELISA
- Assay PrecisionIntra-Assay CV: 5.2%; Inter-Assay CV: 7.0%
- Assay Sensitivity0.39 ng/ml
- Assay SpecificityThere is no detectable cross-reactivity with other relevant proteins.
- Assay Time~ 5 hours
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
- Storage Instruction2°C to 8°C
- UNSPSC41116133