Anti-Ms CD44 APC

EXBIO

Rat Monoclonal to CD44

7

Flow cytometry: Recommended dilution: 1 microg/ml; positive control: murine peripheral blood.

Flow Cytometry

Research Use Only

IM7

0.5 mg/ml

APC (Allophycocyanin)

IgG2b

CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.

2°C to 8°C

12352203