Rat Phospho-CDK1/2 (Thr14) Ready-To-Use IHC Kit

Bioss

Rat Phospho-CDK1/2 (Thr14) Ready-To-Use IHC Kit

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ImmunoHistoChemistry

Research Use Only

CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.

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