Bio-Connect
WB analysis of GTX00343-pro Rat VEGFA protein (active).
WB analysis of GTX00343-pro Rat VEGFA protein (active).
WB analysis of GTX00343-pro Rat VEGFA protein (active).

Rat VEGFA protein (active)

Research Use Only
GTX00343-PRO
GeneTex
ApplicationsFunctional Assay
Product group Proteins / Signaling Molecules
Protein IDP16612
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Rat VEGFA protein (active)
  • Delivery Days Customer
    9
  • Applications
    Functional Assay
  • Certification
    Research Use Only
  • Conjugate
    Unconjugated
  • Protein IDP16612
  • Protein Name
    Vascular endothelial growth factor A
  • Scientific Description
    This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352202

References

  • COX2 Enhances Neovascularization of Inflammatory Tenocytes Through the HIF-1alpha/VEGFA/PDGFB Pathway. Deng B et al., 2021, Front Cell Dev Biol
    Read more