RbAp48 antibody [11G10]

GeneTex

RbAp48 antibody [11G10]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Functional Assay, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking

Research Use Only

Monoclonal

11G10

1 mg/ml

Unconjugated

RBBP4

RB binding protein 4, chromatin remodeling factor

NURF55, RBAP48, lin-53, histone-binding protein RBBP4, CAF-1 subunit C, CAF-I 48 kDa subunit, CAF-I p48, MSI1 protein homolog, RBBP-4, chromatin assembly factor 1 subunit C, chromatin assembly factor I p48 subunit, chromatin assembly factor/CAF-1 p48 subunit, nucleosome-remodeling factor subunit RBAP48, retinoblastoma-binding protein 4, retinoblastoma-binding protein p48

Mouse

IgG2b

Histone-binding protein RBBP4

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203