Western Blot Positive WB detected in: Mouse skeletal muscle tissue All lanes: RBL1 antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 121, 115 kDa Observed band size: 121 kDa

RBL1 Antibody

Name: RBL1 Antibody
SKU: CSB-PA019398LA01HU_C90
Availability: BackOrder

CSB-PA019398LA01HU

ApplicationsWestern Blot, ELISA

Product group Antibodies

ReactivityHuman, Mouse

TargetRBL1

Overview

Supplier
Cusabio
Product Name
RBL1 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID5933
Target name
RBL1
Target description
RB transcriptional corepressor like 1
Target synonyms
107 kDa retinoblastoma-associated protein; CP107; p107; PRB1; retinoblastoma-like 1; retinoblastoma-like protein 1
Host
Rabbit
Isotype
IgG
Protein IDP28749
Protein Name
Retinoblastoma-like protein 1
Scientific Description
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 Lys-20 trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

RBL1 Antibody

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Overview

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