RBM4 Polyclonal Antibody

Reddot Biotech

RBM4 Polyclonal Antibody

5

0.72 mg/ml

RBM4

RNA binding motif protein 4

LARK; lark homolog; RBM4A; RNA-binding motif protein 4a; RNA-binding protein 4; transcriptional coactivator CoAZ; ZCCHC21; ZCRB3A; zinc finger CCHC-type and RNA binding motif 3A

RBM4,RNA-binding motif protein4,contains 2 RRM-type RNA-binding motif and a retroviral-type(RT) zinc finger. RNA-binding factor participates in number of aspects of cellular processes such as alternative splicing of pre-mRNA and translation regulation. RBM4 recruits eIF4A1 to stimulate IRES-dependent translation in responds to cellular stress. Once assembled at the rHRE,the HIF2A-RBM4-eIF4E2 complex captures the 5-prime cap and targets mRNAs to polysomes for active translation,thereby evading hypoxia-induced repression of protein synthesis.

-20°C

12352203