RBM5 antibody
GTX129783
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetRBM5
Overview
- SupplierGeneTex
- Product NameRBM5 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10181
- Target nameRBM5
- Target descriptionRNA binding motif protein 5
- Target synonymsG15; H37; LUCA15; LUCA-15; putative tumor suppressor LUCA15; renal carcinoma antigen NY-REN-9; RMB5; RNA-binding protein 5
- HostRabbit
- IsotypeIgG
- Protein IDP52756
- Protein NameRNA-binding protein 5
- Scientific DescriptionComponent of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5 and 3 splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203