Rebaudioside A [58543-16-1]

Chemodex

Rebaudioside A [58543-16-1]

10

58543-16-1

Research Use Only

>98%

C44H70O23

967.01

Chemical. CAS: 58543-16-1. Formula: C44H70O23. MW: 967.01. Rebaudioside A is a glucosylated steviol glycoside studied and used as a non-glycemic sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. Rebaudioside A is a alpha-glucosidase inhibitor with (IC50=35microg/ml) and can inhibit ATP-sensitive K+-channels. In vitro rebaudioside A stimulated the insulin secretion from MIN6 cells in a dose- and glucose-dependent manner. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. Rebaudioside A is metabolized by gut microbiota to steviol. Rebaudioside A shows antioxidant activity on reducing cellular reactive oxygen species. It is an activator of Nrf2 and is a potential candidate hepatoprotective agent. - Rebaudioside A is a glucosylated steviol glycoside studied and used as a non-glycemic sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. Rebaudioside A is a alpha-glucosidase inhibitor with (IC50=35microg/ml) and can inhibit ATP-sensitive K+-channels. In vitro rebaudioside A stimulated the insulin secretion from MIN6 cells in a dose- and glucose-dependent manner. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. Rebaudioside A is metabolized by gut microbiota to steviol. Rebaudioside A shows antioxidant activity on reducing cellular reactive oxygen species. It is an activator of Nrf2 and is a potential candidate hepatoprotective agent.

C=C1[C@@]2(O[C@H]3[C@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O5)[C@H](O)[C@@H](CO)O3)C[C@]6(C1)CC[C@]7([H])[C@](C)(C(O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)=O)CCC[C@@]7(C)[C@]6([H])CC2

RT

12352200