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ProductsBack/Rebeccamycin [93908-02-2]
Chemical Structure
Chemical Structure
Chemical Structure

Rebeccamycin [93908-02-2]

Research Use Only
BVT-0139
BioViotica
CAS Number93908-02-2
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Product group Chemicals
Estimated Purity>98%
Molecular Weight570.4
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Overview

  • Supplier
    BioViotica
  • Product Name
    Rebeccamycin [93908-02-2]
  • Delivery Days Customer
    10
  • ADR Class
    6.1
  • CAS Number
    93908-02-2
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C27H21Cl2N3O7
  • Molecular Weight
    570.4
  • Scientific Description
    Antibiotic. Structurally similar to staurosporine. Selective activity against several cancer cell lines. DNA intercalator, resulting in catalytic inhibition of topoisomerases I. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells). Does not show any inhibitory activity against protein kinases. - Chemical. CAS: 93908-02-2. Formula: C27H21Cl2N3O7. MW: 570.4. Isolated from Streptomyces sp. Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells).
  • SMILES
    COC1C(O)C(O)C(OC1CO)N1C2=C3NC4=C(C=CC=C4Cl)C3=C3C(=O)NC(=O)C3=C2C2=C1C(Cl)=CC=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UN Number
    UN 3462
  • UNSPSC
    12352200