Bio-Connect

Recombinant Human CD40

232340
Aurora Biolabs
Product group Proteins
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Aurora Biolabs
  • Product Name
    Recombinant Human CD40
  • Delivery Days Customer
    12
  • Category Supplier
    Protein
  • Certification
    Research Use Only
  • Scientific Description
    The human CD40 extracellular domains, consisting of amino acids 1-193, with a Avi tag linked to a C-terminal 10x-histidine sequence. CD40 is a receptor protein found on the surface of immune cells, including B cells, dendritic cells, and macrophages. It plays an important role in regulating immune responses, particularly in the activation and proliferation of B cells. When CD40 is activated by its ligand, CD154, it leads to the upregulation of costimulatory molecules and cytokine production, promoting an effective immune response. Dysregulation of the CD40/CD154 pathway has been implicated in various autoimmune and inflammatory disorders, as well as cancer. Targeting this pathway has therapeutic potential for these diseases.
  • Storage Instruction
    -80⁰C
  • UNSPSC
    12352202