More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Recombinant Human Her2/ERBB2 Protein (ECD), HPLC-verified
Loaded Herceptin on ProA Biosensor, can bind Recombinant Human Her2 / ERBB2 Protein, no Tag (Cat. No. 10004-HCCH) with an affinity constant of 1.8 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested).
Loaded Herceptin on ProA Biosensor, can bind Recombinant Human Her2 / ERBB2 Protein, no Tag (Cat. No. 10004-HCCH) with an affinity constant of 1.8 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested).
Loaded Herceptin on ProA Biosensor, can bind Recombinant Human Her2 / ERBB2 Protein, no Tag (Cat. No. 10004-HCCH) with an affinity constant of 1.8 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested).

Recombinant Human Her2/ERBB2 Protein (ECD), HPLC-verified

Research Use Only
10004-HCCH
Sino Biological
DownloadDatasheet
DownloadMSDS
Product group Molecular Biology
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Sino Biological
  • Product Name
    Recombinant Human Her2/ERBB2 Protein (ECD), HPLC-verified
  • Delivery Days Customer
    10
  • Category Supplier
    Her2/ERBB2 Proteins
  • Certification
    Research Use Only
  • Scientific Description
    Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
  • UNSPSC
    12352204

References

  • Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.
    Read more

Related products

Product group Molecular Biology
Sino Biological
Recombinant Human Her2/ERBB2 Protein (ECD, His Tag), Amine-Labeled Biotinylated10004-H08H4-B
  • SizePrice
Product group Molecular Biology
Sino Biological
Recombinant Human Her2/ERBB2 Protein (His & AVI Tag), Biotinylated, HPLC-verified10004-H27H-B
  • SizePrice
Product group Molecular Biology
Sino Biological
Recombinant Human Her2/ERBB2 Protein (ECD, His Tag), Amine-Labeled Biotinylated, HPLC-verified10004-H08H-B
  • SizePrice
Product group Molecular Biology
Sino Biological
Recombinant Human Her2/ERBB2 Protein (ECD, domain IV, His Tag)10004-H08H4
  • SizePrice
Product group Molecular Biology
Sino Biological
Recombinant Human Her2/ERBB2 Protein (hFc Tag), Amine-Labeled Biotinylated10004-H02H-B
  • SizePrice
Product group Molecular Biology
Sino Biological
Recombinant Human Her2/ERBB2 Protein (ECD, His Tag), Amine-Labeled Biotinylated10004-H08H1-B
  • SizePrice
Product group Molecular Biology
Sino Biological
Recombinant Human Her2/ERBB2 Protein (ECD), Biotinylated, HPLC-verified10004-HCCH-B
  • SizePrice
Product group Antibodies
Sino Biological
Recombinant Anti-Her2/ERBB2 Antibody (Biotin), Rabbit Monoclonal10004-R002A-B
  • SizePrice
Product group Antibodies
Sino Biological
Recombinant Anti-Her2/ERBB2 Antibody (Biotin), Rabbit Monoclonal10004-R205-B
  • SizePrice
Product group Antibodies
Sino Biological
Recombinant Anti-Her2/ERBB2 Antibody (Biotin), Rabbit Monoclonal10004-R511-B
  • SizePrice