Recombinant Human IGF2BP2

Applied Biological Materials

Recombinant Human IGF2BP2

9

Research Use Only

IGF2 mRNA-binding protein 2 (IGF2BP2), also known as IMP2, was found to be an HMGA2 target gene during early embryonic development. IGF2BP2 belongs to a family of RNA-binding proteins that contain six characteristics of RNA-binding modules, including two N-terminal RNA recognition motifs (RRM1 and RRM2) and four C-terminal hnRNP K-homology (KH1&KH4) domains. Its homolog, IGF2BP1/IMP1, has been shown to be essential for normal embryonic growth and development.

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