Recombinant human IL-13, His (HEK293), Biotin Conjugated
BS-43536P-BIOTIN
Protein IDP20109
Product group Proteins / Signaling Molecules
Overview
- SupplierBioss
- Product NameRecombinant human IL-13, His (HEK293), Biotin Conjugated
- Delivery Days Customer16
- CertificationResearch Use Only
- ConjugateBiotin
- Estimated Purity>90%
- Gene ID16163
- Target nameIl13
- Target descriptioninterleukin 13
- Target synonymsIl-13, interleukin-13, T-cell activation protein P600
- Protein IDP20109
- Protein NameInterleukin-13
- Scientific DescriptionThis gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
- Storage Instruction-80°C
- UNSPSC41116120
- SpeciesMouse, Other Species