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Recombinant Human IL1B

Z100395
Applied Biological Materials
Product group Proteins / Signaling Molecules
10 ug
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Overview

  • Supplier
    Applied Biological Materials
  • Product Name
    Recombinant Human IL1B
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Monocytes are the main source of secreted IL1; expressing mostly IL1B, while human keratinocytes express large amounts of IL1A. Overall, IL1B is the predominant form in humans while, IL1A is the one in mice. Both isoforms of IL1 bind to the same receptor and therefore show similar, if not identical, biological activities. The IL1B precursor though must be processed before it can bind to the receptor. IL1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. A monomer, IL1B stimulates thymocyte proliferation, B-cell maturation and proliferation and fibroblast growth factor activity.
  • Storage Instruction
    -20°C,-80°C,2°C to 8°C
  • UNSPSC
    12352202

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