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Recombinant Human IL3

Z100515
Applied Biological Materials
Product group Proteins / Signaling Molecules
10 ug
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Overview

  • Supplier
    Applied Biological Materials
  • Product Name
    Recombinant Human IL3
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    IL3 is produced mainly by T cells following cell activation by antigens and mitogens, but also by keratinocytes, natural killer cells, mast cells, endothelial cells, and monocytes. The analysis of bacterial- derived recombinant IL3 shows that glycosylation is not required for activity. IL3 sequences are evolutionarily less well conserved with human and murine IL3 sharing approximately 29% homology (at the protein level) and murine and rat IL3 sharing approximately 54% homology. IL3 receptors are expressed on macrophages, mast cells, eosinophils, megakaryocytes, basophils, bone marrow progenitor cells and various myeloid leukemia cells. Binding of IL3 to its receptor causes specific phosphorylation of a 150 kDa membrane glycoprotein. Recombinant human IL3 is a non-glycosylated globular protein.
  • Storage Instruction
    -20°C,-80°C,2°C to 8°C
  • UNSPSC
    12352202

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