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Recombinant Human Noggin (NOG)

Z100925
Applied Biological Materials
Product group Proteins / Signaling Molecules
20 ug
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Overview

  • Supplier
    Applied Biological Materials
  • Product Name
    Recombinant Human Noggin (NOG)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Noggin is a secreted homodimeric glycoprotein that binds to ligands of the TGF-beta family (BMPs) and regulates their activity by inhibiting their access to signaling receptors. Mature human Noggin protein contains an N-terminal acidic region, a central basic heparin-binding segment and a C-terminal cysteine knot structure. Noggin binds different BMPs with variable affinities, antagonizing specific BMPs during skeletal development. Noggin is expressed in defined areas of the adult central nervous system and peripheral tissues such as lung, skeletal muscle and skin.
  • Storage Instruction
    -20°C,-80°C,2°C to 8°C
  • UNSPSC
    12352202

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