Recombinant mouse IL-10 protein, N-His Tag (HEK293), Biotin Conjugated
BS-43113P-BIOTIN
Protein IDP18893
Product group Proteins / Signaling Molecules
Overview
- SupplierBioss
- Product NameRecombinant mouse IL-10 protein, N-His Tag (HEK293), Biotin Conjugated
- Delivery Days Customer16
- CertificationResearch Use Only
- ConjugateBiotin
- Estimated Purity>90%
- Gene ID16153
- Target nameIl10
- Target descriptioninterleukin 10
- Target synonymsCSIF, If2a, Il-10, interleukin-10, cytokine synthesis inhibitory factor, interferon 2a
- Protein IDP18893
- Protein NameInterleukin-10
- Scientific DescriptionThe protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]
- Storage Instruction-80°C
- UNSPSC41116120
- SpeciesMouse, Other Species