Recombinant mouse IL-1b protein, C-His
BS-41073P
ApplicationsELISA
Product group Proteins / Signaling Molecules
Protein IDP10749
Overview
- SupplierBioss
- Product NameRecombinant mouse IL-1b protein, C-His
- Delivery Days Customer16
- ApplicationsELISA
- CertificationResearch Use Only
- ConjugateUnconjugated
- Estimated Purity>95%
- Gene ID16176
- Target nameIl1b
- Target descriptioninterleukin 1 beta
- Target synonymsIL-1beta, Il-1b, interleukin-1 beta, IL-1 beta, interleukin 1b
- Protein IDP10749
- Protein NameInterleukin-1 beta
- Scientific DescriptionThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
- Storage Instruction-80°C
- UNSPSC41116120
- SpeciesMouse, Other Species