RecombinantIL-1beta,Porcine

Biorbyt

RecombinantIL-1beta,Porcine

10

Reconstituted in ddH2O or PBS at 100 microg/ml.

Research Use Only

>95%

Interleukin-1 beta (rpIL-1beta) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. IL-1alpha and IL-1beta are structurally related polypeptides that share approximately 27% amino acid (aa) identity in porcine. While IL-1alpha and IL-1beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1beta stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity.Recombinant Porcine IL-1beta produced in E.coli is a single non-glycosylated polypeptide chain containing 154 amino acids. A fully biologically active molecule, rpIL-1beta has a molecular mass of 17.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.

E.coli

-20°C,-80°C,2°C to 8°C

12352202