Refametinib

MedChem Express

Refametinib [923032-37-5]

10

923032-37-5

Research Use Only

99.82

C19H20F3IN2O5S

572.34

Refametinib (BAY 869766; RDEA119) is an orally available, potent, non-ATP-competitive, selective, allosteric MEK1/MEK2 inhibitor with IC50s of 19 nM and 47 nM, respectively.

O=S(C1(C[C@H](O)CO)CC1)(NC(C(NC(C(F)=C2)=CC=C2I)=C3F)=C(OC)C=C3F)=O

-20°C,2°C to 8°C

12352200