Regorafenib-13C,d3

MedChem Express

Regorafenib-13C,d3

10

Research Use Only

C20 13CH12D3ClF4N4O3

486.83

Regorafenib- 13 C,d 3 is the 13 C- and deuterium labeled Regorafenib. Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRbeta, Kit, RET and Raf-1, respectively.

O=C(N[13C]([2H])([2H])[2H])C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1

12352200