Regorafenib [BAY 73-4506] [755037-03-7]

AdipoGen Life Sciences

Regorafenib [BAY 73-4506]

10

755037-03-7

Research Use Only

>98%

Warning

C21H15ClF4N4O3

482.8

Chemical. CAS: 755037-03-7. Formula: C21H15ClF4N4O3. MW: 482.8. Orally bioavailable potent antitumor, antiangiogenic, antiproliferative and antineoplastic agent. Multi-target kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, Kit, RET and Raf-1 with IC50 values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively. - Orally bioavailable potent antitumor, antiangiogenic, antiproliferative and antineoplastic agent. Multi-target kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, Kit, RET and Raf-1 with IC50 values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.

CNC(=O)C1=CC(OC2=CC(F)=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)=CC=N1

-20°C,2°C to 8°C

12352200