Regorafenib (monohydrate)
HY-10331A
CAS Number1019206-88-2
Product group Chemicals
Estimated Purity99.96
Molecular Weight500.83
Overview
- SupplierMedChem Express
- Product NameRegorafenib (monohydrate) [1019206-88-2]
- Delivery Days Customer10
- CAS Number1019206-88-2
- CertificationResearch Use Only
- Estimated Purity99.96
- Molecular FormulaC21H17ClF4N4O4
- Molecular Weight500.83
- Scientific DescriptionRegorafenib (BAY 73-4506) monohydrate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRbeta , Kit , RET and Raf-1 , respectively. Regorafenib monohydrate shows very robust antitumor and antiangiogenic activity [1] .
- SMILESO=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F.O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200