Regorafenib (monohydrate) (Standard)
HY-10331AR
Product group Assays
Overview
- SupplierMedChem Express
- Product NameRegorafenib (monohydrate) (Standard) [1019206-88-2]
- Delivery Days Customer999
- CAS Number1019206-88-2
- CertificationResearch Use Only
- Molecular FormulaC21H17ClF4N4O4
- Molecular Weight500.83
- Scientific DescriptionRegorafenib (monohydrate) (Standard) is the analytical standard of Regorafenib (monohydrate). This product is intended for research and analytical applications. Regorafenib (BAY 73-4506) monohydrate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRbeta, Kit, RET and Raf-1, respectively. Regorafenib monohydrate shows very robust antitumor and antiangiogenic activity[1].
- SMILESO=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F.O
- UNSPSC12352200