rel-(R,R)-THC

MedChem Express

rel-(R,R)-THC

5

138090-06-9

Research Use Only

C22H24O2

320.42

rel-(R,R)-THC is the relative configuration of (R,R)-THC (HY-103451). (R,R)-THC is an ERalpha agonist and an ERbeta antagonist, with Kis of 9.0 nM and 3.6 nM for ERalpha and ERbeta, respectively. (R,R)-THC has higher relative binding affinity for ERbeta than ERalpha with the values of 25 and 3.6[1].

CC[C@H]1C2=C([C@@H](CC3=CC(O)=CC=C32)CC)C4=CC=C(O)C=C4C1

12352200