Relacorilant

MedChem Express

Relacorilant

5

Research Use Only

99.12

C27H22F4N6O3S

586.56

Relacorilant is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a K i of 7.2 nM in HepG2 TAT assay, and also shows K i s of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively. Relacorilant has the potential for Cushings syndrome treatment.

O=C(C1=CC(C(F)(F)F)=CC=N1)[C@@]2(CN(S(=O)(C3=CN(C)N=C3)=O)CC4)C4=CC5=C(C=NN5C6=CC=C(F)C=C6)C2

-20°C,2°C to 8°C

12352200