Remdesivir de(ethylbutyl 2-aminopropanoate)

Biorbyt

Remdesivir de(ethylbutyl 2-aminopropanoate)

10

Research Use Only

98.00%

C18H18N5O7P

447.34

Remdesivir de(ethylbutyl 2-aminopropanoate) is a recognized impurity in Remdesivir, a nucleoside analog demonstrating potent antiviral efficacy. It exhibits EC50 values of 74 nM against SARS-CoV and MERS-CoV in human airway epithelial (HAE) cells, and 30 nM against murine hepatitis virus in delayed brain tumor cells. Notably effective in vitro against SARS-CoV-2 (COVID-19) infection, Remdesivir has garnered attention for its application in controlling the spread of the virus, as supported by references [1] [2].

Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)Oc2ccccc2)[C@@H](O)[C@H]1O)C#N

-20°C

12352200