Remdesivir impurity 9-d4

MedChem Express

Remdesivir impurity 9-d4

10

Research Use Only

C27H31D4N6O8P

606.6

Remdesivir impurity 9-d4 is deuterium labeled Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

O=C(OCC(CC)CC)[C@@](C([2H])([2H])[2H])([2H])N[P@](OC1=CC=CC=C1)(OC[C@H]2O[C@@](C#N)(C3=CC=C4C(N)=NC=NN43)[C@H](O)[C@@H]2O)=O

See Manual

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