Remodelin [949912-58-7]

MedChem Express

Remodelin [949912-58-7]

10

949912-58-7

Research Use Only

99.92

C15H14N4S

282.36

Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model[1][2][3][4].

N#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1

2°C to 8°C

12352200