Renin inhibitor-1 [1093082-54-2]

MedChem Express

Renin inhibitor-1 [1093082-54-2]

10

1093082-54-2

Research Use Only

C22H30N4O4

414.50

Renin inhibitor-1 (compound 26) is a potent and orally active renin inhibitor with IC50s of 0.9, 1.8 nM for rh-renin and hPRA, respectively. Renin inhibitor-1 shows antihypertensive efficacy. Renin inhibitor-1 has the potential for the research of hypertension and cardiovascular/renal diseases[1].

O=C(OC)NCCCN1C=C(CN(C2CC2)C([C@H]3CNCCO3)=O)C4=C1C=CC=C4

12131703