RENT1 antibody

GeneTex

RENT1 antibody

7

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IP: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

UPF1

UPF1 RNA helicase and ATPase

HUPF1, NORF1, RENT1, UTF, pNORF1, smg-2, regulator of nonsense transcripts 1, ATP-dependent helicase RENT1, UPF1 regulator of nonsense transcripts homolog, delta helicase, nonsense mRNA reducing factor 1, smg-2 homolog, nonsense mediated mRNA decay factor, up-frameshift mutation 1 homolog, up-frameshift suppressor 1 homolog, yeast Upf1p homolog

Rabbit

IgG

Regulator of nonsense transcripts 1

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203