Repotrectinib

MedChem Express

Repotrectinib [1802220-02-5]

10

1802220-02-5

Research Use Only

99.90

C18H18FN5O2

355.37

Repotrectinib (TPX-0005) is a potent ROS1 ( IC 50 =0.07 nM) and TRK ( IC 50 =0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK ( IC 50 =1.01 nM). Repotrectinib has anti-cancer activity [1] [2] .

O=C1NC[C@H](C)OC2=CC=C(F)C=C2[C@@H](C)NC3=NC4=C1C=NN4C=C3

-20°C,2°C to 8°C

12352200