Resibufogenin [465-39-4]

TargetMol Chemicals

Resibufogenin [465-39-4]

9

465-39-4

Chemical

Research Use Only

Resibufogenin

98.78%

C24H32O4

384.51

1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogeninas major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5beta-hydroxylation .

3 years

CC12CCC3C(CCC4CC(O)CCC34C)C11OC1CC2c1ccc(=O)oc1

-20°C

12352200