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Resiquimod

M7189
AbMole BioScience
CAS Number144875-48-9
Product group Chemicals
Molecular Weight314.38
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Resiquimod
  • Delivery Days Customer
    9
  • CAS Number
    144875-48-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C17H22N4O2
  • Molecular Weight
    314.38
  • Scientific Description
    Resiquimod (R-848) is a agonist of Toll-like receptors 7 and 8 (TLR7/TLR8) that induces upregulation of cytokines such as TNF-alfa, IL-6 and IFN-alfa. R848 (Resiquimod) induces differential TLR7 and/or TLR8 responses in human and murine immune cells. R848 (Resiquimod) acts as a selective activating ligand for both TLR7 and TLR8 in humans but only TLR7 in mice. It activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway with the subsequent activation of the transcription factors NF-kappaB and interferon regulatory factor (IRF).
  • SMILES
    CCOCC1=NC2=C([N]1CC(C)(C)O)C3=C(C=CC=C3)N=C2N
  • UNSPSC
    12352200