RET-IN-16 [2259657-48-0]
HY-146710
Overview
- SupplierMedChem Express
- Product NameRET-IN-16 [2259657-48-0]
- Delivery Days Customer10
- CAS Number2259657-48-0
- CertificationResearch Use Only
- Molecular FormulaC31H29F3N8O2
- Molecular Weight602.61
- Scientific DescriptionRET-IN-16 is a potent and selective RET inhibitor with IC50s of 3.98 nM, 8.42 nM, 15.05 nM, 7.86 nM, 5.43 nM and 8.86 nM for RET(WT), RET(M918T), RET(V804L), RET(V804M), RET-CCDC6 and RET-KIF5B, respectively. RET-IN-16 has anticancer effects[1].
- SMILESCC1=CC=C(C=C1OC2=C3C=NNC3=NC(C4=CN=CC=C4)=N2)C(NC5=CC(C(F)(F)F)=C(C=C5)CN6CCN(CC6)C)=O
- UNSPSC12131703