Bio-Connect

RET-IN-16 [2259657-48-0]

HY-146710
MedChem Express
CAS Number2259657-48-0
Product group Chemicals
Molecular Weight602.61
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RET-IN-16 [2259657-48-0]
  • Delivery Days Customer
    10
  • CAS Number
    2259657-48-0
  • Certification
    Research Use Only
  • Molecular Formula
    C31H29F3N8O2
  • Molecular Weight
    602.61
  • Scientific Description
    RET-IN-16 is a potent and selective RET inhibitor with IC50s of 3.98 nM, 8.42 nM, 15.05 nM, 7.86 nM, 5.43 nM and 8.86 nM for RET(WT), RET(M918T), RET(V804L), RET(V804M), RET-CCDC6 and RET-KIF5B, respectively. RET-IN-16 has anticancer effects[1].
  • SMILES
    CC1=CC=C(C=C1OC2=C3C=NNC3=NC(C4=CN=CC=C4)=N2)C(NC5=CC(C(F)(F)F)=C(C=C5)CN6CCN(CC6)C)=O
  • UNSPSC
    12131703